Complex Regional Pain Syndrome

Reading this article

Topic pages summarize public health information in plain language. They may describe common causes and treatments in general terms; your own plan of care depends on your clinician’s exam, history, and tests. Use what you read here to prepare questions—not to start, stop, or change medications or to self-diagnose.

Complex regional pain syndrome (CRPS) is a chronic pain condition. It causes intense pain, usually in the arms, hands, legs, or feet. It may happen after an injury, either to a nerve or to tissue in the affected area. Rest and time may only make it worse.

Symptoms in the affected area are:

  • Dramatic changes in skin temperature, color, or texture
  • Intense burning pain
  • Extreme skin sensitivity
  • Swelling and stiffness in affected joints
  • Decreased ability to move the affected body part

The cause of CRPS is unknown. There is no specific diagnostic test. Your doctor will diagnose CRPS based on your signs and symptoms.

There is no cure. It can get worse over time, and may spread to other parts of the body. Occasionally the symptoms go away, either temporarily or for good. Treatment focuses on relieving the pain, and can include medicines, physical therapy, and nerve blocks.

NIH: National Institute of Neurological Disorders and Stroke